Welcome to the EF-CLIF web-page, the main working tool of our investigators. All protocols of the multicenter prospective observational studies and randomized controlled trials performed by our network of Hospitals and their clinical research forms are loaded in the reserved research area of the webpage. You will find in other areas detailed information related to the organization, rules, steering committees, research facilities and scientific production as well as the past and the future educational activities of the EF CLIF.



Performs clinical studies to improve the diagnosis and treatment of patients with Chronic Liver Failure (CLIF).



Promote translational research studies in Chronic Liver Failure (CLIF).



April 18th 2018 Anna Bosch has been appointed Managing Director of the EF Clif Anna Bosch holds a PhD with a doctoral thesis in molecular genetics and developed translational research on diabetes during several years, between the Genetics Department of the University of Barcelona and the Tumor and Biology Centre in the Karolinska Institute, Sweden. In 1998 she incorporated to the IDIBAPS to create the biobank of the Esther Koplowitz Medical Research Center at the Hospital Clinic Campus. Subsequently her responsibilities extended to other biobanks of the Campus and scientific core facilities including genomics, bioinformatics and biostatistics, flow cytometry, cerebral imaging through MRI and P3 laboratory.

The change is aimed to prepare the Foundation to major challenges coming in the near future, including a significant increase in the number of projects and funds, the participation of the Foundation in EU grants and the incorporation of high throughput omics technology in most observational studies and projects.

April 16th 2018 NEWS FROM THE EASL CLIF CONSORTIUM GENERAL ASSEMBLY AND STEERING COMMITTEE During the EASL International Liver Congress 2018 at Paris, the EASL Clif Consortium held the Annual General Assembly and the Steering Committee meeting

More than 80 investigators of the EASL Clif Consortium took part in the Assembly where the speakers gave a comprehensive overview of the latest researches in the setting of EF Clif and had the opportunity to exchange experiences.

February 07th 2018 Welcome to Paolo Angeli as the new Chairman of the EASL-CLIF Consortium The EF Clif organized an international meeting at the foundation headquarters, on February 7th 2018, to welcome Paolo Angeli as the new Chairman of the EASL-Clif Consortium (January 1st 2018)

Among the participants, there were most Steering Committee Members of the EASL-CLIF Consortium, a selected group of investigators from the PREDICT Study, the Principal Investigators of the 2018 research program of the EF Clif, members of the Grifols Chair, Dr Tom Henning Karlsen, EASL General Secretary, Professors Roger Williams and Flair Carrilho

December 21th 2017 Dr Alberto Farias has visited the EF Clif headquarters Associate Professor of Gastroenterology and Hepatology at the Sao Paulo University Medical School, he is the Clinical Coordinator of the Liver Transplant Program at the Hospital das Clínicas and the Project Manager of the EF Clif sponsored ACLARA study.

His four-days stage at the EF Clif headquarters served to start coordinating efforts in the ACLARA Study preparation, following the plan designed at the PI's meeting held in Sao Paulo last September.

November 13th 2017 NEWS FROM THE GRIFOLS CHAIR #3 Addressing patients' diversity in acutely decompensated cirrhosis Richard Moreau, Joan Clària and Vicente Arroyo

The CANONIC study has shown that among patients with acute decompensation (AD) of cirrhosis, those who had Acute-on-Chronic Liver Failure (ACLF, characterized by intense systemic inflammation, organ failures and poor outcome) were clearly distinct from those with traditional AD (who do not have organ failures and have good outcome).