STUDIES

CLINICAL TRIAL
ONGOING RECRUITMENT

REP COVID

Plasma Exchange in patients with COVID-19 disease and invasive mechanical ventilation: a randomized study

PRINCIPAL INVESTIGATORS Javier Fernández, Joan Clària EUDRACT: 2020-001722-66
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

DECISION

Decompensated Cirrhosis: Identification of new Combinatorial therapies based on system approaches.

DECISION is also active on twitter and Linkedin. Please all follow the project!

PRINCIPAL INVESTIGATORS Pierre-Emmanuel Rautou Website
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

MICROB-PREDICT

MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response.

PRINCIPAL INVESTIGATORS Jonel Trebicka Website
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

ACLARA STUDY

Prevalence, epidemiology, characterization and mechanisms of Acute-on-Chronic Liver Failure (ACLF) in Latin America

PRINCIPAL INVESTIGATORS Vicente Arroyo, Flair Carrilho, Alberto Farias, Richard Moreau Website
OBSERVATIONAL STUDY

PREDICT STUDY

Predicting Acute-on-Chronic Liver Failure in Cirrhosis. Multicenter, prospective, observational study will be performed in centers that belong to the European Foundation for the Study of Chronic Liver failure (EF-CLIF)-European Association for Study of the Liver (EASL)-EASL-CLIF Consortium.

PRINCIPAL INVESTIGATORS Jonel Trebicka Website
CLINICAL TRIAL

SCotCH

Supplemental Corticosteroids in Cirrhotic Hypotensive Patients with Suspicion of Sepsis
Randomized controlled trial on the efficacy and safety of low dose cortisone in the treatment of hypotensive Cirrhotic Patients with suspicion of sepsis

PRINCIPAL INVESTIGATORS Alexander Wilmer Philippe Meersseman & Julia Wendon EUDRACT: 2010-024273-38 Website
CLINICAL TRIAL

INFECIR2

Randomized controlled trial on the effects of albumin administration in patients with advanced cirrhosis and bacterial infections other than Spontaneous Bacterial Peritonitis (SBP)

PRINCIPAL INVESTIGATORS Javier Fernández EUDRACT: 2013-002416-27 Website
CLINICAL TRIAL

CANONIC Ancillaries

CANONIC Ancillary Studies approved by the CLIF Steering Committee

PRINCIPAL INVESTIGATORS List of the studies canonic-ancillary-studies.pdf
OBSERVATIONAL STUDY

CANONIC

Assess the diagnostic criteria, prevalence, clinical features, prognosis and mechanisms of Acute on Chronic Liver Failure in cirrhosis

PRINCIPAL INVESTIGATORS Richard Moreau Protocol of the CLIF Acute-oN-ChrONic Liver F canonic-crf.pdf