STUDIES

CLINICAL TRIAL

A-TANGO

Novel treatment of acute-on-chronic liver failure using synergistic action of G-CSF and TAK-242 Twitter LinkedIn

PRINCIPAL INVESTIGATORS Rajiv Jalan Website
OBSERVATIONAL STUDY

ACLARA

Prevalence, epidemiology, characterization and mechanisms of Acute-on-Chronic Liver Failure (ACLF) in Latin America

PRINCIPAL INVESTIGATORS Flair José Carrilho
Richard Moreau
Website
OBSERVATIONAL STUDY

CANONIC

Assess the diagnostic criteria, prevalence, clinical features, prognosis and mechanisms of Acute on Chronic Liver Failure in cirrhosis

PRINCIPAL INVESTIGATORS Richard Moreau Protocol of the CLIF Acute-oN-ChrONic Liver F canonic-crf.pdf
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

CHANCE

Liver transplantation in patients with cirrhosis and severe acute-on-chronic liver failure: Indications and outcomes

PRINCIPAL INVESTIGATORS Thierry Gustot
William Bernal
Javier Fernandez
Elizabet A. Pomfret
Mohamed Rela
Didier Samuel

Scientific Coordinator: Rajiv Jalan
NCT 04613921
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

COBALT

COVID-19 vaccination and biomarkers in cirrhosis and post-liver transplantation

PRINCIPAL INVESTIGATORS Gautam Mehta
OBSERVATIONAL STUDY
ONGOING RECRUITMENT

DECISION

Decompensated cirrhosis: Identification of new combinatorial therapies based on system approaches

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PRINCIPAL INVESTIGATORS Pierre-Emmanuel Rautou Website
CLINICAL TRIAL

INFECIR2

Randomized controlled trial on the effects of albumin administration in patients with advanced cirrhosis and bacterial infections other than Spontaneous Bacterial Peritonitis (SBP)

PRINCIPAL INVESTIGATORS Javier Fernández EUDRACT: 2013-002416-27 Website
OBSERVATIONAL STUDY

MICROB-PREDICT

Microbiome-based biomarkers to predict decompensation of liver cirrhosis and treatment response

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LinkedIn

PRINCIPAL INVESTIGATORS Jonel Trebicka Website
OBSERVATIONAL STUDY

PREDICT

Predicting acute-on-chronic liver failure in cirrhosis

PRINCIPAL INVESTIGATORS Jonel Trebicka Website
CLINICAL TRIAL
ONGOING RECRUITMENT

REP-COVID

Plasma exchange in patients with COVID-19 disease and invasive mechanical ventilation: A randomized study

PRINCIPAL INVESTIGATORS Javier Fernández
Joan Clària
EUDRACT: 2020-001722-66
CLINICAL TRIAL

SCOTCH

Supplemental corticosteroids in cirrhotic hypotensive patients with suspicion of sepsis

PRINCIPAL INVESTIGATORS Alexander Wilmer
Philippe Meersseman
Julia Wendon
EUDRACT: 2010-024273-38 Website
CLINICAL TRIAL

CANONIC Ancillaries

CANONIC Ancillary Studies approved by the CLIF Steering Committee

PRINCIPAL INVESTIGATORS List of the studies canonic-ancillary-studies.pdf