No ACLF
a) No organ failure
b) One organ failure (liver, coagulation, circulatory, respiratory) with creatinine < 1.5 mg/dL and no HE
c) Single cerebral failure and creatinine< 1.5 mg/dL
ACLF grade 1
a) Single kidney failure
b) Single liver, coagulation circulatory or respiratory failure + creatinine 1.5-1.9 mg/dL and/or HE I-II
c) Single cerebral failure (HE III-IV) + creatinine 1.5-1.9 mg/dL
ACLF grade 2 2 organ failures
ACLF grade 3 3 or more organ failurescore